Build a compliant,
submission-ready protocol, fast.

The 1-stop intelligent workspace that takes protocols from design through lifecycle,accelerating first-patient-in.
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NVIDIA Inception Partner

Protocol development is slow, chaotic, and risky.

4+ months

Months lost to version chaos

Endless loops

Reviews back and forth

Hidden risks

Surface late as costly amendments

90%of trials miss enrollment goals
80%of trials miss their timelines

Blind spots burn budget and stall enrollment.

Sources: Tufts CSDD, Deloitte, PhRMA, McKinsey.

We understand the pressure of getting to first-patient-in without sacrificing scientific rigor, so we built the Hub AI-native, not just AI-powered.

Legacy tools bolt AI on after the fact. Avenio builds intelligence into the protocol itself. The protocol thinks with you.

Trained on 25,000+ protocols

and 70B+ clinical parameters, across therapeutic areas

Deterministic, low-hallucination

Consistent, auditable outputs with human oversight

Compliant by design

ICH/FDA aligned; 21 CFR Part 11 audit trail; your data never trains our models

From concept to submission-ready in three steps.

1

Draft with AI

Align each section with built-in clinically trained AI guidance

2

Collaborate

Bring every stakeholder into one collaborative workspace

Where we win3

Surface risk

Risk Radar flags inconsistencies and risks with resolution paths

Start with a single protocol and see the difference within days.

Protocols that reach first-patient-in faster.

28%

Faster first-patient-in

40%

Fewer amendments

50%

Less authoring time

$120K+

Saved per protocol

Avoid the budget burn, blind spots, and downstream delays of manual protocol development.

One hub, every stakeholder.

Clinical Development

Faster, higher-quality protocols, fewer amendments

Medical Writers

Draft from intelligence, not a blank page

Regulatory

ICH/FDA alignment and 21 CFR Part 11 by design

Biostatistics

Consistent endpoints, criteria, and schedules

Each role gets value on day one.

The Intelligent Protocol Hub is AI-native by design.

AI-Powered

AI bolted onto legacy protocol workflows

  • AI requires a new skill, 'prompt engineering,' to draft
  • AI after errors surface in review
  • AI after costly amendments
  • AI catches risk downstream
  • AI waits for the process.
Intelligent Protocol Hub is AI-Native

Avenio AI: intelligence built into the protocol

  • Draft: AI aligns each section at design
  • De-risk: risks & gaps caught as you write, at source
  • Collaborate: real-time, version-controlled
  • Comply: ICH/FDA misalignments surfaced proactively
  • The protocol thinks with you.

28%faster first-patient-in

Secure and compliant by design.

Data isolation

Your data stays in your instance, never used to train models. Bring your own cloud (GCP or AWS).

21 CFR Part 11

Native audit trail, e-signatures, and version lineage built into the workflow.

SOC 2 & HIPAA

Certification in progress; architected for regulated environments from day one.

Teams are already winning with Avenio.

A nerve center for clinical trial design... cuts weeks off the Concept to First-Patient-In timeline.

Haytham E., CMO · G2, 5★

Domain-specific intelligence... handles structured and unstructured data smoothly. Setup was very easy and straightforward.

Nigel G., Clinical Operations Leader · G2, 5★

Start with a single protocol.
See the difference in days.

Request demo

Frequently asked questions

FAQ: Product & workflow

FAQ: Security & IT

FAQ: Commercial